Back

Percutaneous aspiration for shortening time to blood cultures sterilization in right-sided infective endocarditis and vegetations

Polo, F. T.; Nakhle, A.; Gnall, E.; Rozenbaum, Z.

2024-06-13 infectious diseases
10.1101/2024.06.12.24308736 medRxiv
Show abstract

BackgroundSurgical intervention is associated with earlier clearance of bacteremia in infective endocarditis (IE). AimWe hypothesized that vegetectomies using percutaneous aspiration shortens time to sterilization of blood cultures in patients with right-sided IE and vegetations. ResultsThe cohort included 37 patients, 23 treated conservatively, and 14 underwent percutaneous vegetectomy. The median time to blood culture sterilization among patients with bacteremia over 7 days, was 16.5 (IQR 9.75-29) for patients treated conservatively and 11.5 (IQR 8.5-11.5) for those who underwent vegetectomy. The 2 patients who required mechanical ventilation were among the vegetectomy group, and the single patient who died during the same admission was treated conservatively. There were no complications in the vegetectomy group. ConclusionThese data are hypothesis-generating, suggesting that utilizing percutaneous aspiration in patients with right-sided IE and vegetations shortens time to sterilization of blood cultures, and possibly improves outcomes.

Matching journals

The top 13 journals account for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.