Antimalarial Drug Resistance in Plasmodium falciparum from Tak Province, Thailand (1998-2001): A TaqMan Array Card Study.
Thaloengsok, S.; Chaisatit, C.; Saingam, P.; Lertsethakarn, P.; Spring, M.; Sriwichai, S.; Pholwat, S.; Guler, J. L.; Houpt, E.; Vesely, B. A.
Show abstract
Despite declining malaria cases in Thailand, surveillance in endemic areas is crucial. Retrospectively analyzing samples from Tak province, Thailand, we found prevalent drugresistant Plasmodium falciparum, particularly to mefloquine and sulfadoxine/pyrimethamine. Notably, mutations indicating resistance to artemisinin were detected at low frequencies, suggesting evolving resistance. These findings stress the need for continuous surveillance to guide control strategies and prevent outbreaks, even with decreasing cases, to sustain malaria elimination efforts.
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