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Precision medicine for pandemics: stratification of COVID-19 molecular phenotypes defined by topological analysis of global blood gene expression.
2024-04-15
infectious diseases
Title + abstract only
View on medRxiv
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Precision medicine offers a promising pathway for improving therapeutic responses to pandemics like COVID-19. This study utilises independent patient cohorts from Florence and Liege, collected under the DRAGON consortium, to classify molecular phenotypes associated with COVID-19 through topological analysis of whole blood gene expression. Samples from 173 patients were collected, and RNA was sequenced using the Novaseq platform. Molecular phenotypes were identified through topological analysis o...
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