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Glycosylation state of vWF in circulating extracellular vesicles serves as a novel biomarker for predicting depression.

2024-03-26 psychiatry and clinical psychology Title + abstract only
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The clinical diagnosis of major depressive disorder (MDD), a heterogeneous disorder, still depends on subjective information in terms of various symptoms regarding mood. Detecting extracellular vesicles (EVs) in blood may result in finding a diagnostic biomarker that reflects the depressive stage of patients with MDD. Here, we report the results on the glycosylation pattern of enriched plasma EVs from patients with MDD and age-matched healthy subjects. In this cohort, the levels of Triticum vulg...

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