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The extent and impact of vaccine status miscategorisation on covid-19 vaccine efficacy studies

2024-03-16 allergy and immunology Title + abstract only
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It is recognised that many observational studies and randomised control trials reporting high efficacy for Covid-19 vaccines suffer from various biases. Systematic review identified thirty-seven studies that suffered from one particular and serious form of bias called miscategorisation bias, whereby study participants who have been vaccinated are categorised as unvaccinated up to and until some arbitrarily defined time after vaccination occurred. Simulation demonstrates that this miscategorisati...

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