Investigation of Two-Component Hydrogel System for the Tissue Regeneration from Simulation
Jiang, S.; Kumar, E.
Show abstract
Tissue degenerative diseases pose significant global health challenges. Currently, hydrogel therapy stands as a promising approach to address these conditions. To explore its potential, we developed a computational simulation model to mimic hydrogel behavior accurately and precisely measure its degradation rate while incorporating dynamics associated with cell growth. This model aimed to investigate the relationship between a two-component hydrogel system and cell growth, assessing its feasibility for tissue regeneration. Our analysis revealed that the nutritional support for neural stem cells exceeds that of bone marrow cells, followed by other types of cells. This is significant considering the challenge in culturing neural stem cells compared to the relative ease of culturing other cell types. Additionally, we found that there isnt a single solution to determine the optimal conditions for cell growth. Different tissue regeneration processes require distinct conditions to establish what could be considered as suitable growth environments. Lastly, its important to note that these suitable conditions can be fine-tuned by adjusting various parameters.
Matching journals
The top 8 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Hyaluronic Acid on the Urokinase Sustained Release with a Hydrogel System Composed of Poloxamer 407: Enhanced Stability of Intracellular Interaction by Adding HA. 94%
- Interaction between β-lactoglobulin and EGCG under high-pressure by molecular dynamics simulation 93%
- Rapid High-Throughput Isolation and purification of Chicken Myoblasts Based on Deterministic Lateral Displacement Microfluidic Chips 93%
Similar papers in this journal
- Development of a 3D vascular network visualization platform for one-dimensional hemodynamic simulation 92%
- Classification of dog breeds using convolutional neural network models and support vector machine 91%
- Ventricular and Atrial Pressure-Volume Loops: Analysis of the Effects Induced by Right Centrifugal Pump Assistance 90%
Similar papers in this journal
- Electrospun cellulose acetate/gelatin nanofibrous wound dressing containing berberine for diabetic foot ulcer healing: in vitro and in vivo studies 95%
- Nonlinear Dispersive Cell Model for Microdosimetry of Nanosecond Pulsed Electric Fields 93%
- Model Parameter identification using 2D vs 3D experimental data: a comparative analysis 93%
Similar papers in this journal
- Synergistic effects of conductivity and cell-imprinted topography of chitosan-polyaniline based scaffolds for neural differentiation of adipose-derived stem cells 92%
- Engineering a GelMA-dECM-Based 3D Bioprinted Liver Fibrosis Model: Methotrexate-Induced Functional and Molecular Validation 92%
- Molecular Structure Study on the Polyelectrolyte Properties of Actin Filaments 92%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.