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Does cardiorespiratory fitness mediate or moderate the association between mid-life physical activity and cognitive function? Findings from the 1958 British birth cohort study
2023-11-17
epidemiology
Title + abstract only
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BackgroundPhysical activity (PA) is associated with a lower risk of cognitive decline and all-cause dementia in later life. Pathways underpinning this association are unclear but may involve either mediation and/or moderation by cardiorespiratory fitness (CRF). MethodsData on participation in PA (exposure) at 42y, non-exercise testing CRF (NETCRF, mediator/moderator) at 45y and overall cognitive function (outcome) at 50y were obtained from 9,385 participants in the 1958 British birth cohort stu...
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