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Retrospective study of botulinum neurotoxin for hemifacial spasm - experience over 25 years.

Lee, M. K. K.

2023-10-03 neurology
10.1101/2023.10.03.23296410 medRxiv
Show abstract

IntroductionHemifacial spasm (HFS) is a not uncommon, debilitating movement disorder. This retrospective study examines 25 years of experience with Botulinum neurotoxin (BoNT) injections for HFS in Malaysia. ObjectiveTo assess BoNTs long-term effectiveness in treating HFS in a private practice. MethodsData from 35 patients, including demographics, treatment outcomes, and complications, were collected from a private clinic over 25 years. ResultsBoNT demonstrated a decreasing dose trend over time, with extended treatment intervals. Complications were rare and transient, with high patient retention. ConclusionBoNT is a safe and effective long-term HFS treatment, enhancing accessibility in private practice, complementing public healthcare services.

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