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Identifying X-Chromosome Variants Associated with Age-Related Macular Degeneration
2023-08-31
genetic and genomic medicine
Title + abstract only
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PurposeIn genome-wide association studies (GWAS), X chromosome (ChrX) variants are often not investigated. Sex-specific effects and ChrX-specific quality control (QC) are needed to examine these effects. Previous analyses identified 52 autosomal variants associated with age-related macular degeneration (AMD) via the International AMD Genomics Consortium (IAMDGC), but did not analyze ChrX. Therefore, our goal was to investigate ChrX variants for association with AMD. MethodsWe genotyped 29,629 n...
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