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Expression Of Variability Of The Cyp2C19*2 Gene In Patients With Acute Myocardial Infarction From A South American Hospital And Its Future Relevance In The Interaction Between Genetics And Cardiology.

2023-08-20 genetic and genomic medicine Title + abstract only
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IntroductionSome Polymorphisms of the CYP2C19 gene are associated with a decrease in the activity of the enzyme they encode, being the case of CYP2C19*2 in causing a lower generation of active metabolite of clopidogrel and therefore a low or null antiplatelet action depending on the genotype present. Antiplatelet therapy, mainly clopidogrel, is considered essential treatment in the management of acute coronary syndromes (ACS). TargetThe frequency of the CYPC19*2 polymorphism, identified as rele...

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