Back

Diffusion-limited O2 release in human kidneys perfused with stored blood

2023-05-10 transplantation Title + abstract only
View on medRxiv
Show abstract

A central dogma in physiology is that oxygen release at tissues is not diffusion-limited because gas exchange at capillaries is rapid. This assertion has influenced clinical care, which focuses on optimising oxygen delivery through improving blood flow and oxygen content, rather than oxygen unloading from red blood cells (RBCs). Since storage of blood causes profound changes that slow oxygen release from RBCs, transfusions could compromise tissue respiration. We investigated this in transplant h...

Predicted journal destinations

1
PLOS ONE
1737 training papers
Top 34% 19.4%
2
Scientific Reports
701 training papers
Top 7% 16.1%
3
Journal of Clinical Medicine
77 training papers
#1 13.0%
4
Journal of the American Society of Nephrology
19 training papers
Top 0.8% 4.6%
5
BMJ Open
553 training papers
Top 35% 4.6%
6
Journal of Clinical Investigation
50 training papers
Top 1% 2.1%
7
Frontiers in Medicine
99 training papers
Top 10% 1.7%
8
eLife
262 training papers
Top 27% 1.7%
9
Frontiers in Immunology
140 training papers
Top 8% 1.5%
10
Nature Communications
483 training papers
Top 44% 1.5%
11
Cureus
64 training papers
Top 15% 1.0%
12
Science Translational Medicine
40 training papers
Top 3% 1.0%
13
Cell Reports Medicine
49 training papers
Top 5% 1.0%
14
iScience
74 training papers
Top 9% 1.0%
15
JCI Insight
63 training papers
Top 8% 0.8%
16
Journal of the American Heart Association
92 training papers
Top 15% 0.5%
17
Cancers
57 training papers
Top 9% 0.5%
18
Medicine
29 training papers
Top 9% 0.5%
19
Heliyon
57 training papers
Top 20% 0.5%
20
Microbiology Spectrum
86 training papers
Top 9% 0.5%
21
JAMA Network Open
125 training papers
Top 39% 0.5%
22
PLOS Digital Health
88 training papers
Top 24% 0.5%
23
eClinicalMedicine
55 training papers
Top 9% 0.5%
24
Diagnostics
36 training papers
Top 8% 0.5%
25
Blood Advances
16 training papers
Top 1% 0.5%