Risk of SARS-CoV-2 reinfection is time- and variant-dependant, France, January 2021 to August 2022
Auvigne, V.; Schaeffer, J.; Boudon, T.; Tamandjou, C.; Figoni, J.; Parent du Chatelet, I.; Bernard-Stoecklin, S.
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Since the emergence of Omicron, reinfections with SARS-CoV-2 have been rising. We estimated the risk of SARS-CoV-2 reinfection in the widely vaccinated French population, from January to August 2022. At nine weeks post-infection, the relative risk of reinfection, primary infection with pre-Delta variants being the reference group, was estimated at 0.43 [95%CI 0.40-0.47] if the primary infection was attributed to Delta, 0.21 [95%CI 0.19-0.24] with BA.1 and 0.17 [95% CI 0.15-0.18] with BA.2, and rapidly waned overtime. After a BA.1 primary infection the protection was similar against BA.2 or BA.4/5 reinfection.
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