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The TH01 microsatellite and INS VNTR are strongly associated with type 2 diabetes and fasting insulin secretion
2022-09-25
endocrinology
Title + abstract only
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AbstractA variable number of tandem repeats (VNTR) located in the insulin gene (INS) control region may be involved in the development of type 2 diabetes (T2D). The TH01 microsatellite is located close to INS and has previously been suggested to be involved its regulation. Therefore, this observational study investigated whether the TH01 microsatellite and INS VNTR, as assessed via the surrogate marker single nucleotide polymorphism (SNP) rs689, are associated with T2D in the Mexican population....
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