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Prevalence of various inappropriate antibiotic doses among pediatric patients of in-patient, out-patient, and emergency care units in Bangladesh: a cross-sectional study

Islam, A. F. M. M.; Raihan, M. A.; Emran, M. G. I.; Ahmed, K. T.; Nusrat, N. A.; Hasan, M. A.; Ahmed, T.; Lamisa, A. B.; Happy, H. A.; Khatoon, M. M.

2022-06-26 pediatrics
10.1101/2022.06.21.22276716 medRxiv
Show abstract

Antibiotics are the most frequently recommended medications for the treatment of bacterial infections. In most instances, pediatric patients have been prescribed antibiotics without a suitable dosage. Furthermore, existing antibiotic dosages in the market are not appropriate for pediatric patients. As a result, the complication brought on by antibiotic resistance increases day by day. This study was conducted to examine and evaluate the appropriateness of antibiotic doses. This study used a convenient sampling method to collect 300 filled prescription orders from heterogeneous pediatric patients prescribed by physicians from three different patient care departments: emergency patient care, inpatient care, and outpatient care, of various clinics, hospitals, and health care centers. There were 165 male responders and 135 female respondents in all. This study rated the 12 most prevalent diseases diagnosed in pediatric patients of various ages. This study revealed that prescribers recommended antibiotic overdoses for patients in the outdoor unit and that antibiotic underdoses were more prevalent among pediatric patients in the outdoor unit. According to this finding, it is straightforward to conclude that prescribers underestimated the doses and could not change the dosage for kids of early childhood and toddler age. Unfamiliar prescribers with the correct pediatric dose standards may have committed prescription dosing errors repeatedly, leading to the development of multi-drug resistance. More research can be conducted on these antibiotics effects or potential adverse effects on pediatric patients.

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