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Factors influencing Blacks and Whites participation in Alzheimers disease biomarker research

Eliacin, J.; Hathaway, E.; Wang, S.; O'Connor, C.; Saykin, A.; Cameron, K.

2022-05-12 psychiatry and clinical psychology
10.1101/2022.05.03.22274625 medRxiv
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INTRODUCTIONAlzheimers disease (AD) is a public health priority. AD biomarkers may vary based on race, but recruitment of diverse participants has been challenging. METHODSThree groups of Black and White participants with and without prior research advocacy or participation were interviewed individually or in focus groups to better understand perspectives related to AD biomarker research participation. Thematic analytic approach was used to analyze the data. RESULTSIdentified barriers to AD biomarker research participation included hesitancy due to fear, distrust of research and researchers, lack of relevant knowledge, and lack of research test results disclosure. Drivers for engagement in biomarker research procedures included knowledge about research, AD, and related clinical procedures, perceived benefits of participation, and outreach from trusted sources. DISCUSSIONParticipants comments related to the need for diversity in research and desire for results disclosure suggest opportunities to engage Black individuals.

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