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Effectiveness of COVID-19 mRNA vaccine booster dose relative to primary series during a period of Omicron circulation

Petrie, J. G.; King, J. P.; McClure, D. L.; Rolfes, M. A.; Meece, J. K.; Belongia, E. A.; McLean, H. Q.

2022-04-16 epidemiology
10.1101/2022.04.15.22273915 medRxiv
Show abstract

During a period of Omicron variant circulation, we estimated relative VE of COVID-19 mRNA booster vaccination versus primary two-dose series in an ongoing community cohort. Relative VE was 66% (95% CI: 46%, 79%) favoring the booster dose compared to primary series vaccination. Our results support current booster recommendations.

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