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Clinical and Economic Impact of COVID-19 on Plantation Workers: Preliminary Results from the Guatemala Agricultural Workers and Respiratory Illness Impact (AGRI) Study

Olson, D.; Calvimontes, D. M.; Lamb, M. M.; Guzman, G.; Barrios, E.; Chacon, A.; Rojop, N.; Arias, K.; Gomez, M.; Bolanos, G. A.; Monzon, J.; Chard, A. N.; Iwaomto, C.; Duca, L. M.; Vuong, N.; Fineman, M.; Lesteberg, K.; Beckham, D.; Santiago, M. L.; Quicke, K.; Ebel, G.; Zielinski Gutierrez, E.; Azziz-Baumgartner, E.; Hayden, F. G.; Mansour, H.; Edwards, K.; Newman, L. S.; Asturias, E. J.

2022-02-08 infectious diseases
10.1101/2022.02.07.22270274 medRxiv
Show abstract

We evaluated the clinical and socioeconomic burdens of respiratory disease in a cohort of Guatemalan banana plantation workers. All eligible workers were offered enrollment from June 15-December 30, 2020, and annually, then followed for influenza-like illnesses (ILI) through: 1) self-reporting to study nurses, 2) sentinel surveillance at health posts, and 3) absenteeism. Workers with ILI submitted nasopharyngeal swabs for influenza, RSV, and SARS-CoV-2 testing, then completed surveys at days 0, 7, and 28. Through October 10, 2021, 1,833 workers developed 169 ILIs (12.0/100 person-years) and 43 (25.4%) of these ILIs were laboratory-confirmed SARS-CoV-2 (3.1/100 person-years). Workers with SARS-CoV-2-positive ILI reported more anosmia (p<0.01), dysgeusia (p<0.01), difficulty concentrating (p=0.01), and irritability (p=0.01), and greater clinical and well-being severity scores (Flu-iiQ) than test-negative ILIs; they also had greater absenteeism (p<0.01) and lost income (median US$127.1, p<0.01). These results support the prioritization of Guatemalan farm workers for COVID-19 vaccination.

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