Clustering analysis based on PiCCO parameters in patients with septic shock
Shen, Y.; Hu, C.; Cai, G.; Yan, J.
Show abstract
The current study identified three septic shock phenotypes according to the pulse index continuous cardiac output parameters: Phenotype-1: normal cardiac output and vascular resistance, high blood volume; Phenotype-2: low cardiac output, normal blood volume, and high vascular resistance. Phenotype-3: normal vascular resistance and blood volume, high cardiac output. The mortality was significantly high in phenotype-1, but comparable between phenotype-2 and phenotype-3 (13/17 (76.4) vs. 13/35 (37.1) vs. 16/46 (34.7), p <0.001). Compared to phenotype 1 and 3, phenotype 2 had a higher AKI incidence and higher creatinine level at discharge.
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