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Analysis of screening results of high-risk population of stroke in Northern Henan Province

Li, Z.; Yang, Q.; Zhang, X.; Guo, Y.; Zhang, J.; Sun, K.; Yang, J.

2022-01-18 neurology
10.1101/2022.01.17.22269405 medRxiv
Show abstract

ObjectivesThrough the screening analysis of stroke population in Northern Henan from 2014 to 2020, to understand the distribution characteristics of high-risk population of stroke and the correlation between high-risk population of stroke and risk factors, to provide basis for stroke prevention and treatment in Northern Henan province. MethodsA random cluster sampling method was used for screening the high-risk population of stroke in Northern Henan Province, and a questionnaire survey, physical examination and laboratory examination were conducted on the respondents (those who lived in the local area for half a year or more) aged above 40 years old who voluntarily participated in and signed the informed consent, and then the data were sorted and analyzed. ResultsA total of 16815 people were participated in screening of high-risk population of stroke in Northern Henan Province, including 6366 males and 10448 females, accounting for 37.86% and 62.14%, respectively; 8855 people were urban household registration, and 7960 people were rural household registration; the age range was 40-80 years old; statistical results demonstrated that there were 3428 people at high-risk of stroke, 3629 people were at moderate risk of stroke, and 8428 people were at low-risk of stroke, accounting for 20.39%, 21.58% and 50.01% in the total screening people, respectively; there were 365 transient Islamic attacks (TIA) patients and 965 stroke patients in the total screening participants in Northern Henan province from 2014 to 2020, accounting for 2.17% and 5.74% in the total screening people, respectively. After further data sorting, we obtained 2588 valid data of high-risk of stroke, there were significant differences in gender, household registration type and age (P<0.01); the incidence rate of high-risk population of stroke was related to dyslipidemia, atrial fibrillation, smoking, lack of exercise, overweight, family history of stroke, hypertension and diabetes mellitus (P<0.01); the top three highest exposure rates of risk factors were diabetes mellitus (67.16%), overweight (62.60%), and lack of exercise (58.27%) in the high-risk population of stroke. A total of 606 valid data of stroke were screened out, there were significant differences in gender and age (P<0.01); the incidence rate of stroke was related to dyslipidemia, smoking, lack of exercise, overweight, stroke family history, hypertension and diabetes mellitus (P<0.01), the top three highest exposure rates of risk factors of stroke were hypertension (73.27%), overweight (42.08%) and lack of exercise (33.83%) in the stroke patients. ConclusionThe incidence rate of stroke high-risk population and stroke patients was lower in Northern Henan Province compared with national average incidence rate in China, and there are statistical differences at gender and age for the incidence rate of stroke high-risk population and stroke patients in Northern Henan Province. There was the highly correlation between risk factors (dyslipidemia, atrial fibrillation, smoking, lack of exercise, overweight, stroke family history, hypertension and diabetes) and stroke high-risk population or stroke. Regular population screening and early prevention should be taken to reduce the incidence rate of stroke.

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