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Transgenic resources for functional studies on the hsrω gene in Drosophila

Sahu, R. K.; Trivedi, D.; Lakhotia, S. C.

2021-12-26 genetics
10.1101/2021.12.26.474178 bioRxiv
Show abstract

The hsr{omega} gene of Drosophila melanogaster, an early discovered non-coding developmentally active and stress-inducible gene, has pleiotropic actions through its multiple nuclear and cytoplasmic non-coding transcripts. With a view to understand this diverse functions and mechanisms of actions of this gene, we generated a series of transgenic lines for over-expression or RNAi of different transcripts and CRISPR-Cas9 mediated deletion alleles. These are described here.

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