Back

Influence of Response Criterion on Nociceptive Detection Thresholds and Evoked Potentials

van den Berg, B.; Vanwinsen, L.; Pezzali, G.; Buitenweg, J. R.

2021-11-04 neuroscience
10.1101/2021.11.02.466896 bioRxiv
Show abstract

Pain scientists and clinicians search for objective measures of altered nociceptive processing to study and stratify chronic pain patients. Nociceptive processing can be studied by observing a combination of nociceptive detection thresholds and evoked potentials. However, it is unknown whether the nociceptive detection threshold measured using a Go-/No-Go (GN) procedure can be biased by a response criterion. In this study, we compared nociceptive detection thresholds, psychometric slopes and central evoked potentials obtained during a GN procedure with those obtained during a 2-interval forced choice (2IFC) procedure to determine 1) if the nociceptive detection threshold during a GN procedure is biased by a criterion and 2) to determine if nociceptive evoked potentials observed in response to stimuli around the detection threshold are biased by a criterion. We found that the detection threshold can be higher when assessed using a GN procedure in comparison with the 2IFC procedure. The average P2 component in the central evoked potential showed on-off behavior with respect to stimulus detection and increased proportionally with the detection probability during a GN procedure. These data suggest that nociceptive detection thresholds estimated using a GN procedure are subject to a response criterion.

Matching journals

The top 10 journals account for 50% of the predicted probability mass.

1
eneuro
● 439 papers in training set
Top 0.5%
7.7%
Similar papers in this journal
2
Scientific Reports
○ 3612 papers in training set
Top 8%
7.1%
Similar papers in this journal
3
NeuroImage
○ 903 papers in training set
Top 3%
5.4%
Similar papers in this journal
4
Psychophysiology
○ 77 papers in training set
Top 0.2%
5.4%
Similar papers in this journal
5
Frontiers in Neuroscience
○ 256 papers in training set
Top 0.5%
5.4%
Similar papers in this journal
6
European Journal of Neuroscience
○ 189 papers in training set
Top 0.5%
5.1%
7
Cortex
○ 119 papers in training set
Top 0.4%
4.8%
8
PLOS ONE
● 5266 papers in training set
Top 32%
4.2%
9
International Journal of Psychophysiology
○ 15 papers in training set
Top 0.1%
3.2%
10
Cerebral Cortex
◐ 396 papers in training set
Top 2%
3.2%
50% of probability mass above
11
Journal of Neuroscience Methods
○ 122 papers in training set
Top 0.6%
3.2%
12
Neuroscience
○ 97 papers in training set
Top 0.3%
3.2%
13
Journal of Neurophysiology
● 302 papers in training set
Top 1%
3.2%
14
Experimental Brain Research
○ 53 papers in training set
Top 0.2%
3.1%
15
Brain Sciences
○ 55 papers in training set
Top 0.4%
2.6%
16
eLife
● 5828 papers in training set
Top 46%
2.1%
17
Journal of Neural Engineering
○ 221 papers in training set
Top 1%
1.7%
18
Brain Research
○ 38 papers in training set
Top 0.3%
1.7%
19
Frontiers in Human Neuroscience
○ 77 papers in training set
Top 1%
1.5%
20
The Journal of Neuroscience
● 1025 papers in training set
Top 8%
1.3%
21
Pain
○ 78 papers in training set
Top 0.7%
1.1%
22
Hearing Research
○ 54 papers in training set
Top 0.3%
1.1%
23
Brain Stimulation
○ 125 papers in training set
Top 0.9%
1.1%
24
Behavioural Brain Research
○ 77 papers in training set
Top 1%
1.1%
25
Heliyon
○ 152 papers in training set
Top 6%
1.0%
26
European Journal of Pain
○ 11 papers in training set
Top 0.2%
1.0%
27
Biological Psychology
○ 21 papers in training set
Top 0.3%
1.0%
28
Imaging Neuroscience
● 282 papers in training set
Top 4%
1.0%
29
Clinical Neurophysiology
○ 56 papers in training set
Top 0.8%
0.9%
30
Journal of Cognitive Neuroscience
● 135 papers in training set
Top 2%
0.8%

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.