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The potential of CYP2D6 phenotyping to improve opioid dosing strategies
2021-10-07
toxicology
Title + abstract only
View on medRxiv
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BackgroundPrescription opioids account for more than 40% of opioid induced mortalities. With the trend towards increased opioid prescribing set to continue rising, opioid-based adverse drug reactions, (ADRs) and their associated human and financial cost present a major global public health concern. The review examined the relationship between CYP2D6 phenotypes and opioid metabolising. The aim was to establish whether screening for CYP2D6 phenotypes would improve existing opioid dosing strategies...
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