Slightly different metabolomic profiles are associated with high or low weights duck foie gras
REMIGNON, H.; LO, B.; Marty-Gasset, N.; Manse, H.; Canlet, C.; Domitile, R.
Show abstract
Understanding the evolution of fatty liver metabolism of ducks is a recurrent issue for researchers and industry. Indeed, the increase in weight during the overfeeding period leads to an important change in the liver metabolism. However, liver weight is highly variable at the end of overfeeding within a batch of animals reared, force-fed and slaughtered in the same way. For this study, we performed a proton nuclear magnetic resonance (1H-NMR) analysis on two classes of fatty liver samples, called low-weight liver (weight between 550 and 599 g) and high-weight liver (weight above 700 g). The aim of this study was to identify the differences in metabolism between two classes of liver weight (low and high). Firstly, the results showed that increased liver weight is associated with higher glucose uptake leading to greater lipid synthesis. Secondly, this increase is probably also due to a decline in the level of export of triglycerides and cholesterol from the liver by maintaining them at high hepatic concentration levels. Finally, the increase in liver weight could lead to a significant decrease in the efficiency of aerobic energy metabolism associated with a significant increase in the level of oxidative stress.
Matching journals
The top 4 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Regulation of amino acid and nucleotide metabolism by crustacean hyperglycemic hormone in the muscle and hepatopancreas of the crayfish Procambarus clarkii 95%
- Candida utilis yeast as a functional protein source for Atlantic salmon (Salmo salar L.): Local intestinal tissue and plasma proteome responses 95%
- Small in size, big on taste: metabolomics analysis of flavor compounds from Philippine garlic 94%
Similar papers in this journal
- Integrative Analysis of Metabolomic and Transcriptomic Profiles Uncovers Biological Mechanism of Feed Efficiency in Pigs 95%
- Effects of Platycodon grandiflorum on Gut Microbiota and Immune System of Immunosuppressed Mouse 94%
- Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke 93%
Similar papers in this journal
Similar papers in this journal
- Molecular liver fingerprint reflects the seasonal physiology of the grey mouse lemur (Microcebus murinus) during winter 94%
- Vagus nerve mediated liver-brain axis is a major regulator of the metabolic landscape in the liver 94%
- Unraveling the Potential Role of Tecomella undulata in Experimental NASH 93%
Similar papers in this journal
- A novel method to detect intracellular metabolite alterations in MCF-7 cells by doxorubicin induced cell death 93%
- Plasma and stool metabolomic biomarkers of non-alcoholic fatty liver disease in Argentina 92%
- Untargeted metabolomics of COVID-19 patient serum reveals potential prognostic markers of both severity and outcome 92%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.