Back

Interim estimates of increased transmissibility, growth rate, and reproduction number of the Covid-19 B.1.617.2 variant of concern in the United Kingdom

Dagpunar, J. S.

2021-06-03 infectious diseases
10.1101/2021.06.03.21258293 medRxiv
Show abstract

This paper relates to data from the Wellcome Sanger Institute, UK, regarding Covid-19 genomic surveillance. We use a simple model to give point estimates of the effective reproduction numbers of the B.1.617.2 and B.1.1.7 lineages in England, from sequenced data as at 15 May 2021. Comparison with the estimated reproduction number of B.1.1.7 enables an estimate of the increased transmissibility of B.1.617.2. We conclude that it is almost certain that there is increased transmissibility that will rapidly lead to B.1.617.2 becoming the prevailing variant in the UK. The derived estimates of increased transmissibility have uncertainty relating to the actual distribution of the generation interval, but they do point, under present conditions of vaccination coverage and NPIs, to exponential growth of positive cases.

Matching journals

The top 4 journals account for 50% of the predicted probability mass.

1
Eurosurveillance
80 papers in training set
Top 0.1%
26.5%
2
Philosophical Transactions of the Royal Society B
51 papers in training set
Top 0.1%
12.6%
3
Scientific Reports
3102 papers in training set
Top 10%
8.4%
4
PLOS ONE
4510 papers in training set
Top 26%
6.5%
50% of probability mass above
5
Emerging Infectious Diseases
103 papers in training set
Top 0.5%
3.7%
6
Epidemics
104 papers in training set
Top 0.7%
2.1%
7
International Journal of Molecular Sciences
453 papers in training set
Top 5%
2.1%
8
Biology Methods and Protocols
53 papers in training set
Top 0.7%
1.8%
9
Royal Society Open Science
193 papers in training set
Top 2%
1.7%
10
Journal of The Royal Society Interface
189 papers in training set
Top 2%
1.7%
11
Epidemiology and Infection
84 papers in training set
Top 2%
1.5%
12
F1000Research
79 papers in training set
Top 2%
1.4%
13
Nature Communications
4913 papers in training set
Top 54%
1.4%
14
Philosophical Transactions of the Royal Society B: Biological Sciences
53 papers in training set
Top 0.6%
1.3%
15
Vaccines
196 papers in training set
Top 2%
1.3%
16
PLOS Computational Biology
1633 papers in training set
Top 21%
1.0%
17
Biology
43 papers in training set
Top 2%
1.0%
18
Journal of Infection
71 papers in training set
Top 2%
1.0%
19
Frontiers in Genetics
197 papers in training set
Top 8%
0.9%
20
GENETICS
189 papers in training set
Top 1%
0.8%
21
PeerJ
261 papers in training set
Top 16%
0.7%
22
Infection, Genetics and Evolution
43 papers in training set
Top 1.0%
0.7%
23
Communications Medicine
85 papers in training set
Top 1%
0.7%
24
Frontiers in Medicine
113 papers in training set
Top 7%
0.7%
25
BMC Infectious Diseases
118 papers in training set
Top 6%
0.7%
26
Mathematical Biosciences and Engineering
23 papers in training set
Top 0.7%
0.7%
27
G3 Genes|Genomes|Genetics
351 papers in training set
Top 3%
0.7%
28
Journal of Theoretical Biology
144 papers in training set
Top 2%
0.7%
29
Wellcome Open Research
57 papers in training set
Top 3%
0.7%
30
Theoretical Population Biology
47 papers in training set
Top 0.2%
0.7%