Back

Epidemiological Profile And Clinical Conditions Of Women With Or Without Precursorlesion For Cervical Cancer

Sampaio, L. M. d. A.; de Franca, L. M. C.; Galvao, C. R.; Galvao, L. R.; Silva, M. E. C.; Dantas, B. M. S.; das Merces, M. C.; Conceicao, S. d. S.; Silva, R. B.; Coelho, J. M. F.

2021-06-02 public and global health
10.1101/2021.05.31.21258126 medRxiv
Show abstract

IntroductionCervical Cancer (CC) in Brazil is the fourth cause of death for malignant neoplasms in female population, being expected to 16,370 new cases for the biennium 2018-2019. ObjectiveTo identify factors associated with the presence of cytopathological changes of the cervix, HIV and/or syphilis in women who performed the Pap Smear (PS) at Family Health Unit (FHU) San Martin, in Salvador-BA, 09 March 2015 to 2018. Materials and methodsThis cross-sectional study consisted of 150 participants. After application of a questionnaire, there was conducted clinical examination of the breast and gynecological and rapid tests for diagnosis of syphilis and HIV types 1 and 2. The bivariate analysis was made by associating each one of the independent variables with the outcome, through contingency tables (Chi-square test and when necessary, the Fishers exact test). The estimates were obtained with Prevalence Ratio (PR) with their 95% confidence intervals (CI 95%) and p values. Mean differences were estimated through Students t-test. The goodness of the test was estimated by ratio of maximum likelihood (p [≤] 0.05). ResultsThere were 11.33% of women with injury and 88.67% without injury. The group with injury (n = 17) presented the worst values in relation to the use of the cigarette (17.65% vs 3.76%) and clinical examination in breast change issues (17.65% vs 4.51%) and unloading (11.76% vs papillary 1.50%), in comparison to the group without precursor lesion pro CC, statistically significant (p [≤] 0.05). 5 cases were positive for syphilis (3.33%), and no case of HIV types 1 and 2. DiscussionThe study confirmed risk factors for injury precursors of CC, such as smoking and mammary changes, as well as how much research related to diverged condom use and reducing the risk of injury and the likely Association with Sexually Transmitted Infections (STI). ConclusionThere was detected a low percentage of women with precursor lesions for the CC (11.33%), that were not associated with syphilis and HIV types 1 and 2, but were correlated the expected factors like mammary changes and smoking. The reorganization of actions of active search of women with risk factors for CC for the EP can culminate in the reduction of this cancer. DescriptorsPap Smear; Precursor Lesion; Cervical Cancer.

Matching journals

The top 3 journals account for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.