Collaborative Cross Founder Expression Analysis (CCFEA)
Green, R. R.; Ireton, R. C.; Ferris, M.; Muenzen, K.; Crosslin, D. R.; Gale, M.
Show abstract
To understand the role of host genetic variation in infection by SARS-CoV and influenza A virus we developed the Collaborative Cross Founder Expression Analysis (CCFEA), a shiny visualization tool using public RNAseq data from the collaborative cross (CC) founder strains (A/J, C57BL/6J, 129s1/SvImJ, NOD/ShILtJ, NZO/HILtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ) that underwent infection by either virus, linked with genetic analyses to define loci linked to infection, immunity, and disease phenotypes. Individual gene expression data is displayed across founders, viral infections and days post infection. Resource Table O_TBL View this table: org.highwire.dtl.DTLVardef@4a284borg.highwire.dtl.DTLVardef@9b6168org.highwire.dtl.DTLVardef@11831baorg.highwire.dtl.DTLVardef@168e351org.highwire.dtl.DTLVardef@123e9ec_HPS_FORMAT_FIGEXP M_TBL C_TBL
Matching journals
The top 3 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Testcrosses are an efficient strategy for identifying cis regulatory variation: Bayesian analysis of allele specific expression (BASE) 93%
- A generic hidden Markov model for multi-parent populations 91%
- Network-based functional prediction augments genetic association to predict candidate genes for histamine hypersensitivity in mice 91%
Similar papers in this journal
Similar papers in this journal
- smalldisco, a pipeline for siRNA discovery and 3' tail identification 91%
- Concerning the eXclusion in human genomics: The choice of sex chromosome representation in the human genome drastically affects number of identified variants 91%
- CDMAP/CDVIS: Context-dependent Mutation Analysis Package and Visualization Software 91%
Similar papers in this journal
- The regulatory architecture of gene expression variation in C. elegans revealed by multi-strain allele-specific analysis 92%
- Single cell Iso-Sequencing enables rapid genome annotation for scRNAseq analysis 91%
- Multiparent Recombinant Inbred lines crossed to a tester provide novel insights into sources of cis and trans regulation of gene expression 91%
Similar papers in this journal
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.