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The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US

Wang, X.; Du, Z.; Johnson, K.; Fox, S.; Lachmann, M.; McLellan, J. S.; Meyers, L. A.

2021-01-20 epidemiology
10.1101/2021.01.18.21250071 medRxiv
Show abstract

As COVID-19 vaccination begins worldwide, policymakers face critical trade-offs. Using a mathematical model of COVID-19 transmission, we find that timing of the rollout is expected to have a substantially greater impact on mortality than risk-based prioritization and uptake and that prioritizing first doses over second doses may be life saving.

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