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Cerebrospinal Fluid Iron Status Predicts Neurocognitive Performance Over Time in Adults with HIV
2020-11-06
hiv aids
Title + abstract only
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Iron homeostasis is essential for brain health, and iron is also required for HIV replication, but the role of iron is largely unexplored in HIV-associated neurocognitive disorders. These disorders remain extremely common in people with HIV, despite antiretroviral therapy capable of suppressing viral replication, and they involve damage to white matter tracts and synaptodendritic architecture in the brain. We hypothesized that cerebrospinal fluid (CSF) levels of iron and two proteins involved in...
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