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Glioblastoma Multiforme: A Meta-Analysis Of Driver Genes, Current Diagnosis, And Tumor Heterogeneity

2020-10-21 oncology Title + abstract only
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Glioblastoma (GBM) is the most aggressive and common brain cancer in adults with the lowest life expectancy. The current neuro-oncology practice has incorporated genes involved in key molecular events that drive GBM tumorigenesis as biomarkers to guide diagnosis and design treatment. This study summarizes findings describing the significant heterogeneity of GBM at the transcriptional and genomic levels, emphasizing eighteen driver genes with clinical relevance. A pattern was identified fitting t...

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