The emergence of inter-clade hybrid SARS-CoV-2 lineages revealed by 2D nucleotide variation mapping
Wang, H.-L.
Show abstract
I performed whole-genome sequencing on SARS-CoV-2 collected from COVID-19 samples at Mayo Clinic Rochester in mid-April, 2020, generated 85 consensus genome sequences and compared them to other genome sequences collected worldwide. I proposed a novel illustrating method using a 2D map to display populations of co-occurring nucleotide variants for intra- and inter-viral clades. This method is highly advantageous for the new era of "big-data" when high-throughput sequencing is becoming readily available. Using this method, I revealed the emergence of inter-clade hybrid SARS-CoV-2 lineages that are potentially caused by homologous genetic recombination.
Matching journals
The top 9 journals account for 50% of the predicted probability mass.
Similar papers in this journal
Similar papers in this journal
- Predicting hosts based on early SARS-CoV-2 samples and analyzing later world-wide pandemic in 2020 95%
- Long-read Assays Shed New Light on the Transcriptome Complexity of a Viral Pathogen and on Virus-Host Interaction 94%
- Chasing the origin of SARS-CoV-2 in Canada's COVID-19 cases: A genomics study 94%
Similar papers in this journal
- VIGA: an one-stop tool for eukaryotic Virus Identification and Genome Assembly from next-generation-sequencing data 95%
- Comparative evaluation of the transmissibility of SARS-CoV-2 variants of concern 95%
- SegFinder: an automated tool for identifying RNA virus genome segments through co-occurrence in multiple sequenced samples 95%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.