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Fractal and inertia moment analysis of SARS CoV-2 proliferation through replication

RAJ, V.; SREEJYOTHI, S.; SWAPNA, M. S.; SANKARARAMAN, S.

2020-10-06 pathology
10.1101/2020.10.03.20206185 medRxiv
Show abstract

The present work proposes a surrogate method for understanding and analyzing the replication of SARS CoV-2 through fractal and inertia moment (IM) analysis of cell culture images at different stages. The fractal analysis of images of cell culture, calculated by the box-counting and power spectral density methods, reflect the stages of virus infection, leading to the replication of the virus RNA and damaging the host cell. The linear increase of IM value reveals not only the proliferation of SARS CoV-2 by replication but also damage to the host cell with time. Thus, the work shows the possibility of fractal analysis and IM measurement for understanding the dynamics of the virus infection.

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