Switched and unswitched memory B cells detected during SARS-CoV-2 convalescence correlate with limited symptom duration

2020-09-05 allergy and immunology Title + abstract only

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Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the pandemic human respiratory illness COVID-19, is a global health emergency. While severe acute disease has been linked to an expansion of antibody-secreting plasmablasts, we sought to identify B cell responses that correlated with positive clinical outcomes in convalescent patients. We characterized the peripheral blood B cell immunophenotype and plasma antibody responses in 40 recovered non-hospitalized COVI...

Switched and unswitched memory B cells detected during SARS-CoV-2 convalescence correlate with limited symptom duration

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