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Metabolomics dissection of depression heterogeneity and related cardiometabolic risk
2020-08-11
epidemiology
Title + abstract only
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BackgroundA recent hypothesis postulates the existence of an "immune-metabolic depression" (IMD) dimension characterized by metabolic dysregulations. Combining data on metabolomics and depressive symptoms, we aimed to identify depressions associated with an increased risk of adverse metabolic alterations. MethodClustering data were from 1094 individuals with current major depressive disorder and measures of 149 metabolites from a 1H-NMR platform and 30 depressive symptoms (IDS-SR30). Canonical ...
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