Double COVID-19 Confirmed Case Fatality Rate in Countries with High Elderly Female Vitamin D Deficiency Prevalence
Backer, A.; Mageswaran, M.
Show abstract
A number of clues point to a possible role of vitamin D in fighting COVID-19: a reduction in case growth speed with solar zenith angle, higher fatality rate in black people, lower fatality rate in populations that spend more time outdoors. Yet a direct demonstration that vitamin D deficiency is associated with COVID-19 fatalities has remained elusive. We show here in a comparison of 32 countries that countries with high prevalence of vitamin D deficiency among elderly females show a confirmed case fatality rate twice as high as those with low prevalence. We then show that this effect cannot be explained by differences in life expectancy between countries. A mechanistic role for vitamin D in the severity of COVID-19 is proposed. One Sentence SummaryVitamin D deficiency among elderly females is associated with countrywide COVID-19 confirmed case fatality rates up to twice as high as those of countries with low vitamin D deficiency prevalence.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
Similar papers in this journal
- A lysosomal dimmer switch regulates cellular quiescence depth 91%
- Pervasive convergent evolution and extreme phenotypes define chaperone requirements of protein homeostasis 91%
- Mutations in thyroid hormone receptor α1 cause premature neurogenesis and progenitor cell depletion in human cortical development 90%
Similar papers in this journal
- Endocrine aryl hydrocarbon receptor signaling is induced by moderate cutaneous exposure to ultraviolet light 91%
- Bridging Pleiotropic Mechanisms in Leprosy Type-1 Reactions and Neurodegenerative diseases 91%
- The demographic and geographic impact of the COVID pandemic in Bulgaria and Eastern Europe in 2020 90%
Similar papers in this journal
- Vitamin D insufficiency and deficiency and mortality from respiratory diseases in a cohort of older adults: potential for limiting the death toll during and beyond the COVID-19 pandemic 91%
- COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/ml 25(OH)D3: Results of a systematic review and meta-analysis 90%
- The Causal Effects of Blood Iron and Copper on Lipid Metabolism Disease: Evidence from Phenome-wide Mendelian Randomization Study 88%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.