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Substitutions in Spike and Nucleocapsid proteins of SARS-CoV-2 circulating in Colombia
2020-06-04
infectious diseases
Title + abstract only
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IntroductionSARS-CoV-2 is a new member of the genus Betacoronavirus, responsible for the COVID-19 pandemics. The virus crossed the species barrier and established in the human population due to its ability to exploit the ACE receptor for virus entry, which is present and abundant in several tissues, including the lung and respiratory tract, gastrointestinal tract and hearth. Virus interaction with the cellular receptor is mediated by the surface protein, known as Spike. Another structural protei...
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