Hyperpyrexia leading to death in a patient with severe COVID-19 disease
Singhal, T.; Phadtare, S.; Pai, S.; Raodeo, A.
Show abstract
We describe here the clinical course of a 42 year old male with severe COVID 19 disease treated at a private hospital in Mumbai, India. This patient with very high inflammatory markers at admission was treated with supportive care, mechanical ventilation, anticoagulation, hydroxychloroquine, corticosteroids, tocilizumab, intravenous insulin, antibiotics, sedation and paralysis. There was sustained improvement in his respiratory status and decline in ventilator settings with decline and normalization of CRP, D dimer and PCT. However high fever persisted that did not respond to paracetamol and NSAIDS. On day 8 of admission his axillary temperature touched 107F followed by rapid clinical deterioration and death within the next 12 hours, Blood cultures were consistently sterile. While death was related to hyperpyrexia, the cause of this hyperpyrexia is uncertain.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Characteristics and outcome profile of Hospitalized African COVID-19 patients: The Ethiopian Context 96%
- Laboratory Biomarkers of COVID-19 Disease Severity and Outcome: Findings from a Developing Country 96%
- COVID-19 Disease Severity and Determinants among Ethiopian Patients: A study of the Millennium COVID-19 Care Center 94%
Similar papers in this journal
- Relative expression of pro-inflammatory molecules in COVID-19 patients manifested disease severities 94%
- Probable causes and risk factors for positive SARS-CoV-2 test in recovered patients: Evidence from Brunei Darussalam 94%
- Risk factors for bacterial infections in patients with moderate to severe COVID-19: A case control study 94%
Similar papers in this journal
- Climate influences scrub typhus occurrence in Vellore, Tamil Nadu, India: Analysis of a 15 year dataset 93%
- Standard blood laboratory results in SARS-CoV-19 positive patients: do they show a typical pattern? 93%
- Emergence of SARS-CoV-2 Omicron Variant JN.1 in Tamil Nadu, India - Clinical Characteristics and Novel Mutations 92%
Similar papers in this journal
- Pulmonary haemorrhage as a frequent cause of death among patients with severe complicated Leptospirosis in Southern Sri Lanka 96%
- Anti-inflammatory cytokine profile and Jarisch-Herxheimer reaction in Leptospirosis patients: a prospective case-series study in New Caledonia 93%
- Health-Related Quality of Life of Adults with Cutaneous Leishmaniasis at ALERT Hospital, Addis Ababa, Ethiopia 92%
Similar papers in this journal
- Determinants of Developing Symptomatic Disease in Ethiopian COVID-19 Patients 94%
- Evaluation of the disease outcome in Covid-19 infected patients by disease symptoms: a retrospective cross-sectional study in Ilam Province, Iran 93%
- Specific Dynamic Variations in the Peripheral Blood Lymphocyte Subsets in COVID-19 and Severe Influenza A Patients: A Retrospective Observational Study 92%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.