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The immune profile of the gut microbiome in graft versus host disease patients

2020-04-11 hematology Title + abstract only
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BackgroundGut microbiota (GM) composition has been associated with acute Graft-versus-Host Disease (aGvHD), however, current knowledge is insufficient to target the GM. MethodsA relevant series of microbiome data sets were combined and reanalyzed, with resolution of species level changes in the GM. ResultsGM composition was found strongly correlated with aGvHD status after one month post stem cell infusion (R2=0.51). The predicted average biological safety level, indicative of antibiotic resis...

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