Restoring Physical Resilience: Consistent Functional and Sarcopenia Gains Across Two Vivifrail Cohorts
Fernandez-Ortega, J.; Loza-Herbella, J.; Rangel-Garcia, J. A.; Fernandez-Revelles, A. B.
Show abstract
Objectives: To evaluate change in physical function and probable sarcopenia following a 36-week community multicomponent exercise programme (Vivifrail model) across two consecutive cycles, and to assess the consistency of this change between cohorts. Study design: Quasi-experimental, single-arm, repeated-measures service evaluation. Ninety-two older adults (2025-2026 cohort; mean age 75.9 years, 88.0% women) completed baseline and post-intervention assessments; an independent 2024-2025 cohort (n = 86) was analysed jointly for replication (n = 178). Main outcome measures: Short Physical Performance Battery (SPPB) score (primary); Timed Up and Go (TUG), handgrip strength, 6-metre walk time and Mini-Mental State Examination (MMSE) (secondary); probable sarcopenia (EWGSOP2), SPPB-based frailty category, and a fall-risk indicator computed identically in both cohorts. Results: SPPB improved by a mean of 1.33 points (Cohen's d = 0.96; p < .001), with concordant improvement in all four secondary outcomes (all q < .005). 72.8% reached the substantial minimal clinically important difference. Probable sarcopenia fell from 17.4% to 5.4% (p = .006), and frailty category shifted toward higher functional levels (p < .001). Effect sizes were consistent between cohorts for SPPB, handgrip and 6-metre walk; the Time x Cohort interaction was significant for TUG only. In the pooled sample, elevated fall risk fell from 19.7% to 11.2% (p = .002). Conclusions: A 36-week multicomponent exercise programme was associated with clinically meaningful, reproducible improvement in physical function and a reduction in probable sarcopenia across two independent cohorts. The single-arm design precludes causal inference.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Home-based Extended Rehabilitation for Older People with Frailty (HERO): a Randomised Controlled Trial 96%
- Frailty is a predictor of medication-related harm requiring healthcare utilisation: a multicentre prospective cohort study 93%
- Frailty trajectories in the oldest old: Is the level or the rate of change more predictive of mortality? 93%
Similar papers in this journal
- The impact of outdoor walking interventions on frailty among older adults with mobility limitations: findings from the Getting Older Adults Outdoors (GO-OUT) study 96%
- Supervised and self-directed technology-based dual-task exercise training programme for older adults at risk of falling – Protocol for a feasibility study 94%
- Validity of the German version of the Stay Independent Questionnaire applied by telephone interview: A diagnostic accuracy study 94%
Similar papers in this journal
- Effects of supervised high-intensity hardstyle kettlebell training on grip strength and health-related physical fitness in insufficiently active older adults: The BELL pragmatic controlled trial 94%
- Frailty and loneliness among community-dwelling older adults: Examining reciprocal associations within a measurement burst design 94%
- Patterns of Physical Activity Over Time in Older Patients Rehabilitating after Hip Fracture Surgery: A Preliminary Study 93%
Similar papers in this journal
- A Bayesian Network Analysis of Gait Speed Change Upon Transition to Uneven Surfaces in Older Adults 95%
- The association of skeletal muscle energetics with recurrent falls in older adults within the Study of Muscle, Mobility and Aging (SOMMA) 93%
- Muscle mitochondrial bioenergetic capacities is associated with multimorbidity burden in older adults: the Study of Muscle, Mobility and Aging (SOMMA) 92%
Similar papers in this journal
- Effect of a simple exercise programme on hospitalisation-associated disability in older patients: a randomised controlled trial. 96%
- Frailty and mortality in hospitalized older adults with COVID-19: retrospective observational study 94%
- Risk factors for falls in community-dwelling older adults: An umbrella review 93%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.