Marker or mechanism? Medical imaging utilisation and population life expectancy in 38 OECD countries, 2000 to 2024 year.
Obuchowicz, R.
Show abstract
Background. Medical imaging is central to modern diagnosis and treatment, yet its contribution to population level survival has rarely been quantified, and the few existing estimates have been interpreted as evidence that imaging directly extends life. Whether national imaging utilisation reflects a distinct clinical mechanism or a broader process of health system development has not been formally tested. Methods. Longitudinal ecological panel study of 38 OECD countries, 2000 to 2024 (950 possible country years). CT and MRI availability and utilisation were linked to life expectancy at birth, treatable and preventable mortality, and seven cause specific mortality outcomes. Two-way fixed-effects models with country and year fixed effects and country clustered standard errors were adjusted sequentially for log GDP per capita, log health expenditure per capita, population aged [≥]65 years, physician density and smoking prevalence. Three falsification families were specified: lead-exposure (placebo) models regressing current life expectancy on future imaging utilisation; negative control exposures with no diagnostic-imaging pathway to survival; and wild cluster bootstrap inference. Results. In the principal adjusted model, CT utilisation at a three year lag was associated with higher life expectancy ({beta} = 0.85 years per 100 additional examinations per 1,000 inhabitants, 95% CI 0.16 to 1.54; cluster robust p = 0.015; bootstrap p = 0.034; n = 339, 29 countries). Scanner availability showed weaker, generally non-significant associations. All three falsification analyses failed to support a modality-specific effect. Future CT utilisation predicted current life expectancy as strongly as past utilisation (three year lead {beta} = 0.86, 95% CI 0.15 to 1.57, p = 0.017), consistent with high within-country autocorrelation of the exposure (r = 0.64 at three years). Radiotherapy equipment density, a therapeutic rather than diagnostic technology, showed an equal and more precise association ({beta} = 0.85 per 10 units per million, 95% CI 0.32 to 1.38, p = 0.0017), as did PET scanner density and health expenditure, whereas physician density showed none. Associations were stronger for preventable ({beta} = -43.3 per 100,000, p = 0.0002) than treatable mortality ({beta} = -13.5, p = 0.19), and all were attenuated to the null under country specific linear trends. Conclusions. National CT utilisation is a robust ecological correlate of life expectancy but does not behave as a causal determinant under falsification. It is best understood as a marker of health system capital development. Claims that imaging adds years of life are not supportable on ecological evidence of this kind.
Matching journals
The top 9 journals account for 50% of the predicted probability mass.
Similar papers in this journal
Similar papers in this journal
- Disentangling the relationship between cancer mortality and COVID-19 88%
- Social Contact Patterns and Implications for Infectious Disease Transmission: A Systematic Review and Meta-Analysis of Contact Surveys 88%
- The impact of COVID-19 on population cancer screening programs in Australia: modelled evaluations for breast, bowel and cervical cancer 88%
Similar papers in this journal
- The confounded crude case-fatality rates for COVID-19 hide more than they reveal - a comparison of age-specific and age-adjusted rates between six countries 89%
- Cost-effectiveness and return on investment of protecting health workers in low- and middle-income countries during the COVID-19 pandemic 88%
- The Mean Unfulfilled Lifespan (MUL): A new indicator of the impact of mortality shocks on the individual lifespan, with application to global 2020 quarterly mortality from COVID-19 88%
Similar papers in this journal
- Estimating and Testing an Index of Bias Attributable to Composite Outcomes in Comparative Studies 88%
- Information bias of vaccine effectiveness estimation due to informed consent for national registration of COVID-19 vaccination: estimation and correction using a data augmentation model 87%
- Income inequality and access to advanced immunotherapy for lung cancer: the case of Durvalumab in the Netherlands 87%
Similar papers in this journal
- Inequalities in healthcare disruptions during the Covid-19 pandemic: Evidence from 12 UK population-based longitudinal studies 89%
- Improvements in the incidence and survival of cancer and cardiovascular but not infectious disease have driven recent mortality improvements in Scotland: nationwide cohort study of linked hospital admission and death records 2001-2016 89%
- What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? - A harmonised, global longitudinal observational study 89%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.