Plasticity of the mutation rate and spectrum in eukaryotic marine phytoplankton
Mettrop, L. A. I.; Lipzen, A.; Vandecasteele, C.; Eche, C.; Sanchez, F.; Labecot, A.; Manirakiza, E.; Barry, K.; Grigoriev, I. V.; Piganeau, G.; Krasovec, M.
Show abstract
The ability to adapt shapes the future of any species or population. Adaptive potential is primarily determined by the spontaneous mutation rate {micro} and the mutation spectrum, which define the new genetic variation available to selection. Increasing evidence points to the plasticity of the mutation rate and spectrum, which vary according to environment. However, data is lacking for marine phytoplankton, an essential group for marine ecosystems as well as a major player in biogeochemical cycles. Here, we measure the plasticity of mutation rates and spectra in the chlorophyte Ostreococcus tauri by mutation accumulation experiments in 4 different conditions: low salinity, high salinity, low temperature, and high temperature. {micro}SNM is lowest under low salinity, doubles under high salinity and low temperature and quadruples under high temperature. SNM spectra become increasingly biased towards C:G[->]T:A transitions with increasing {micro}SNM. While {micro}ID does not change with the environment, the structural mutation rate {micro}SM is higher at low temperature, likely due to transposon activity. Given the rapid environmental changes associated with global climate change, mutation rates and spectra plasticity may critically influence the adaptive potential of marine primary producers.
Matching journals
The top 8 journals account for 50% of the predicted probability mass.
Similar papers in this journal
Similar papers in this journal
- Congruence between noise and plasticity in protein expression 94%
- Identifying the essential genes of Mycobacterium avium subsp. hominissuis with Tn-Seq using a rank-based filter procedure. 94%
- Insights into gene expression changes under conditions that facilitate horizontal gene transfer (mating) of a model Archaeon 93%
Similar papers in this journal
Similar papers in this journal
- Selection for cell yield does not reduce overflow metabolism in E. coli 94%
- Polygenic adaptation, clonal interference, and the evolution of mutators in experimental Pseudomonas aeruginosa populations 93%
- Y-linked copy number polymorphism of target of rapamycin(TOR) is associated with sexual size dimorphism in seed beetles 93%
Similar papers in this journal
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.