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Multiscale harmonization and semantic integration of biomedical data enable biological insights through immersive exploration

Bueckle, A.; Zhu, C.; Wong, A. Y. H.; Enninful, A.; Miao, Y.; Farzad, N.; Pedersen, M.; Mattison, C.; Sloan, N.; Mares, J.; Xing, C.; Herr, B. W.; Khare, J.; Kumar, Y. R.; Parekh, K.; Chavan, S.; Luby, P.; Patel, U.; Hickey, J. W.; Bader, G. D.; Phatnani, H.; Menon, V.; Fan, R.; Sorger, P.; Snyder, M.; Boerner, K.

2026-07-11 bioinformatics
10.64898/2026.07.07.737090 bioRxiv
Show abstract

The Human Reference Atlas (HRA) enables multiscale data exploration and visualization. We present "HRA: Powers of Ten," a virtual reality (VR) application for integrating, harmonizing, and visualizing data within the HRA Organ Gallery. It enables immersive navigation from a whole-body view of 81 organs to datasets across 5 organs, 5 assay types, and 4 spatial scales using a Multiscale Elevator System. The application, data, and code are available open-source.

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