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A near-complete genome assembly of the Fusarium oxysporum keratitis isolate MRL8996

Doddi, A.; Puebla-Planas, G.; Lopez-Berges, M. S.; Di Pietro, A.

2026-07-10 genomics
10.64898/2026.07.06.736765 bioRxiv
Show abstract

Fusarium oxysporum MRL8996 is a fungal strain isolated from a severe case of contact lens-associated keratitis. Here we report a near-complete genome assembly of this isolate using a hybrid Nanopore and Hi-C scaffolding approach. The assembly resolves the genome into 16 distinct chromosomes, including 11 core and 5 lineage-specific chromosomes. This high-quality reference genome provides an unprecedented tool for investigating the large-scale structural variations and evolutionary mechanisms driving adaptation in this highly versatile fungal lineage.

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