Tetradic Dynamics of Dyadic Sensorimotor Coordination: A Multiscale EEG Hyperscanning Study

HighlightsO_LILeader-follower roles structure dyadic coordination mechanisms C_LIO_LIMirroring yields a robust Follower reaction time advantage C_LIO_LITonic-phasic analyses reveal scale-dependent condition asymmetry C_LIO_LIPhasic dynamics resolve into Leader anticipation and Follower post-response inhibition C_LIO_LIIntegrated information decomposition reveals a role-specific inter-brain predictive architecture C_LI How do leader and follower roles shape the brain mechanisms that support coordinated action between people? This question has direct therapeutic relevance for conditions such as schizophrenia and autism spectrum disorder, where the capacity for reciprocal social coordination is a defining vulnerability. Here, we propose a tetradic framework and examine sensorimotor coordination in 16 healthy adult pairs using simultaneous dual-brain EEG hyperscanning, a 2x2 within-subject design crossing Role (Leader/Follower) and Condition (Mirroring/Matching). Mirroring required resonance with a partners movement; Matching required its controlled transformation. This contrast was designed to dissociate automatic from controlled coordination processes across roles. Behaviourally, Mirroring produced a reaction-time advantage that was selective to Followers, a finding replicated in a combined cohort, and consistent with role-dependent attention-inhibition gating. At the neural level, sustained (tonic) activity was dominated by Matching-related frontoparietal engagement regardless of role, while time-resolved (phasic) activity revealed a Mirroring-dominant reorganization that differentiated into role-specific patterns: anticipatory gating in Leaders and post-response inhibitory rebound in Followers. Information-theoretic decomposition of inter-brain coupling identified a Leader-specific predictive signal in medial prefrontal and cingulate cortices, a Follower-specific adaptive signal across sensorimotor and temporal regions, and a shared redundancy scaffold in orbitofrontal and insular cortices. These findings characterize tetradic coordination within dyads as a multiscale, role-asymmetric architecture in which top-down predictive control and bottom-up adaptive regulation are functionally dissociable. The tetradic framework provides an organizing scaffold for this dissociation, and the role-specific signatures it reveals offer candidate biomarkers for clinical populations in whom interpersonal coordination is disrupted.