Back

Weight-Guided Constraints for Body Model and Lead Selection in Pediatric CIED MRI Safety Simulations

Hameed, S.; Henry, K.; Jiang, F.; Bhusal, B.; Dillenbeck, H.; Gakenheimer-Smith, L.; Webster, G.; Golestani Rad, L.

2026-05-30 radiology and imaging
10.64898/2026.05.26.26354162 medRxiv
Show abstract

Pediatric patients with cardiac implantable electronic devices (CIEDs) face limited MRI access due to RF-induced heating, and computational modeling is increasingly used to characterize this risk. The validity of these simulations, however, depends on pairing body models with clinically realistic lead configurations, guidance that is currently lacking. We retrospectively analyzed 302 CIED surgeries in 281 pediatric patients to derive weight-based constraints for simulation design. Weight alone discriminated epicardial from endocardial lead implantation with AUC = 0.90, and adding age and height yielded no improvement, supporting weight as a sufficient single-parameter selection metric. The probabilistic crossover between approaches occurred at 44~kg, substantially higher than the 10 to 15~kg threshold commonly cited in the literature, with a broad transition zone of 21 to 66~kg in which both lead types were routinely used. Lead length was likewise weight-constrained: only 25~cm leads were observed in patients below 6~kg, and leads of 45~cm or longer were uncommon below 50~kg. These findings yield a three-tier framework, with epicardial-only configurations below 21~kg, dual configurations within 21 to 66~kg, and weight-thresholded lead lengths throughout, enabling MRI safety simulations to focus on clinically realizable anatomy and device combinations.

Matching journals

The top 6 journals account for 50% of the predicted probability mass.

1
Scientific Reports
3102 papers in training set
Top 1%
17.7%
2
PLOS ONE
4510 papers in training set
Top 12%
14.9%
3
Journal of Neural Engineering
197 papers in training set
Top 0.5%
6.4%
4
Computers in Biology and Medicine
120 papers in training set
Top 0.4%
4.9%
5
Nature Communications
4913 papers in training set
Top 40%
3.6%
6
Medical Physics
14 papers in training set
Top 0.2%
3.6%
50% of probability mass above
7
Imaging Neuroscience
242 papers in training set
Top 1%
2.6%
8
Human Brain Mapping
295 papers in training set
Top 2%
2.4%
9
Computer Methods and Programs in Biomedicine
27 papers in training set
Top 0.2%
2.1%
10
European Radiology
14 papers in training set
Top 0.3%
2.1%
11
NeuroImage
813 papers in training set
Top 4%
1.7%
12
npj Digital Medicine
97 papers in training set
Top 2%
1.7%
13
Science Advances
1098 papers in training set
Top 18%
1.7%
14
Journal of Magnetic Resonance Imaging
14 papers in training set
Top 0.4%
1.7%
15
NeuroImage: Clinical
132 papers in training set
Top 3%
1.3%
16
Science Translational Medicine
111 papers in training set
Top 3%
1.3%
17
PLOS Computational Biology
1633 papers in training set
Top 19%
1.2%
18
eLife
5422 papers in training set
Top 49%
1.2%
19
Frontiers in Neuroscience
223 papers in training set
Top 5%
1.1%
20
Radiotherapy and Oncology
18 papers in training set
Top 0.2%
1.0%
21
Brain Stimulation
112 papers in training set
Top 1%
1.0%
22
Magnetic Resonance in Medicine
72 papers in training set
Top 0.5%
0.9%
23
International Journal of Radiation Oncology*Biology*Physics
21 papers in training set
Top 0.4%
0.8%
24
JACC: Clinical Electrophysiology
11 papers in training set
Top 0.3%
0.8%
25
Nature Biomedical Engineering
42 papers in training set
Top 2%
0.8%
26
PLOS Global Public Health
293 papers in training set
Top 6%
0.7%
27
Frontiers in Cardiovascular Medicine
49 papers in training set
Top 3%
0.7%
28
iScience
1063 papers in training set
Top 34%
0.7%
29
IEEE Transactions on Neural Systems and Rehabilitation Engineering
40 papers in training set
Top 0.7%
0.7%
30
Journal of Medical Imaging
11 papers in training set
Top 0.4%
0.7%