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High prevalence of soil-transmitted helminth co-infections in persons with tuberculosis in South India

Narasimhan, P. B.; Jain, K.; Rajkumari, N.; Dauphinais, M. R.; Priyanga, J. R.; Shaikh, S.; Patel, J. U.; Babu, S. P.; Cintron, C.; Karoly, M.; Carwile, M. E.; Liu, A. F.; Maloomian, K.; Locks, L. M.; Mehta, S.; Sarkar, S.; Singh, U. B.; Ellner, J. J.; Salgame, P.; Heysell, S. K.; Hochberg, N. S.; Lakshminarayanan, S.; Sinha, P.

2026-06-02 infectious diseases
10.64898/2026.05.26.26353735 medRxiv
Show abstract

Soil-transmitted helminths (STH) are a plausible but under-characterized comorbidity in tuberculosis. In this prospective South Indian cohort, multiplex stool PCR detected STH in 43% of 137 adults with pulmonary tuberculosis and 34% of 230 household contacts. Food insecurity independently predicted co-infection. Current adult deworming gaps warrant evaluation.

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