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Local prevalence of ceftriaxone resistance informs optimal deploy-ment of new gonorrhea treatments

Oliveira Roster, K. I.; Rönn, M. M.; Gorenburg, E. R.; Partl, D. K.; Anderegg, N.; Abel zur Wiesch, P.; Au, C.; Kouyos, R. D.; Martinez, F. P.; Low, N.; Grad, Y. H.

2026-04-24 infectious diseases
10.64898/2026.04.23.26351610 medRxiv
Show abstract

Numerous factors may influence the optimal rollout of new gonococcal antibiotics. We compared eight rollout strategies using a gonorrhea transmission model and ranked strategies by the number of gonococcal infections and clinically useful antibiotic lifespan. Rankings were most sensitive to the starting ceftriaxone resistance prevalence and screening frequency.

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