Back

Natural statistics of host odours predict species-specific olfactory behaviours in Drosophilids

Gong, H.; Ziolkowska, Z.; Khallaf, M. A.; Pop, S.; Ayrton, O.; Cano-Ferrer, X.; MacRae, J.; Knaden, M.; Arguello, R.; Prieto-Godino, L. L.

2026-03-31 neuroscience
10.64898/2026.03.27.714575 bioRxiv
Show abstract

Animals rely on olfaction to locate food, mates, and suitable habitats, yet natural odour environments contain thousands of volatile molecules, creating a high-dimensional sensory problem for both nervous systems and the researchers who study them 1-5. For example, a banana emits around 100 individual volatiles4,6. It remains unclear which components of complex odour blends animals have evolved to use as behavioural cues. Here, combining fieldwork, chemical and behavioural analyses, we show across multiple Drosophila species that behaviourally relevant cues can be predicted directly from the statistical structure of natural odour environments. Animals preferentially respond to components that are most distinctive within their natural host odour blends, and therefore most ecologically informative. These cues can be either major or minor blend components. Our results indicate that host-guided olfactory behaviours have evolved to exploit the statistical structure of natural odour environments by selectively targeting the most informative features of odour blends.

Matching journals

The top 2 journals account for 50% of the predicted probability mass.

1
Nature
575 papers in training set
Top 0.2%
38.3%
2
Nature Communications
4913 papers in training set
Top 13%
12.7%
50% of probability mass above
3
Science Advances
1098 papers in training set
Top 0.1%
10.2%
4
Nature Neuroscience
216 papers in training set
Top 2%
4.4%
5
Current Biology
596 papers in training set
Top 5%
4.0%
6
Nature Biotechnology
147 papers in training set
Top 3%
2.9%
7
iScience
1063 papers in training set
Top 8%
2.5%
8
Proceedings of the National Academy of Sciences
2130 papers in training set
Top 27%
2.1%
9
Cell Reports
1338 papers in training set
Top 22%
1.9%
10
Advanced Science
249 papers in training set
Top 9%
1.9%
11
Communications Biology
886 papers in training set
Top 8%
1.7%
12
eLife
5422 papers in training set
Top 45%
1.5%
13
Nature Methods
336 papers in training set
Top 5%
1.1%
14
Neuron
282 papers in training set
Top 7%
1.0%
15
Nature Ecology & Evolution
113 papers in training set
Top 4%
0.8%
16
Nature Human Behaviour
85 papers in training set
Top 4%
0.8%
17
Science
429 papers in training set
Top 19%
0.8%
18
Nucleic Acids Research
1128 papers in training set
Top 17%
0.8%
19
Proceedings of the Royal Society B: Biological Sciences
341 papers in training set
Top 7%
0.7%
20
Cell
370 papers in training set
Top 18%
0.7%
21
Nature Physics
39 papers in training set
Top 1%
0.5%
22
Nature Aging
51 papers in training set
Top 2%
0.5%
23
National Science Review
22 papers in training set
Top 3%
0.5%
24
PLOS Computational Biology
1633 papers in training set
Top 29%
0.5%