Stakeholder Interest, Power and Operational Capacity Analysis in the Prevention and Control of Genital Chlamydia in Youths 15 to 24 Years Old in Mali and Burkina Faso

Introduction: Chlamydia trachomatis infection is very common in young people aged 15-24 years old in Sub Saharan Africa. Aim: This study aimed to identify key actors involved in the prevention and control of genital chlamydia among young people aged 15-24 and to analyze their positioning and level of commitment to ensure the sustainability and scale-up of the Pfizer Chlamydia Project led by the Faculty of Pharmacy (FAPH). Methods: A quantitative stakeholder analysis was conducted from April 2025 to February 2026, with data collection between September 18, 2025 and January 27, 2026. Stakeholders were evaluated using a standardized grid based on three dimensions: interest (0-20), power/influence (0-12), and operational capacity (0-12). Results: We found high levels of stakeholder interest (13.0-19.0), with RJASR/PF and national coordination structures demonstrating the strongest engagement. Power/influence scores varied widely (5.0-11.5), with national institutions exerting the greatest influence. Operational capacity scores were relatively homogeneous (8.0-11.0). Coefficients of variation indicated low to moderate agreement for interest and operational capacity, but higher variability for power/influence, particularly among community organizations. Discussion: Our findings highlight key partners for strengthening and sustaining chlamydia prevention initiatives in Mali and Burkina Faso. The stakeholder analysis highlights a complementary institutional and community system supporting genital chlamydia prevention among youth in Mali and Burkina Faso. National coordination bodies demonstrated high interest, influence, and operational capacity, confirming their central role in strategic governance and resource mobilization. Technical structures also showed strong capacity for implementing surveillance and screening activities. In contrast, community-based organizations exhibited strong engagement and operational presence but more limited strategic influence, reflecting their field-oriented role in reaching vulnerable youth. Variability in power assessments suggests differing perceptions of institutional influence. Overall, effective project sustainability depends on strengthened collaboration, inclusive governance, and capacity-building to better integrate community actors into decision-making processes.