PerTexP: scenario-based exploration of pertussis dynamics under maternal and infant vaccination
Autoriello, A.; Averga, S.; Buonomo, B.; Della Marca, R.; Guarino, A.; Moracas, C.; Penitente, E.; Poeta, M.
Show abstract
We introduce PerTexP (Pertussis Time Exploration), an interactive modelling tool designed to investigate pertussis transmission dynamics and to support the evaluation of vaccination strategies and short-term projections. PerTexP allows users to explore and compare maternal, infant, and non-infant booster vaccination scenarios and to assess their potential impact on disease transmission, with a particular focus on the Italian epidemiological context. The tool is based on a discrete-time, stage-structured compartmental model with two age classes. By enabling rapid scenario-based analyses, PerTexP supports evidence-informed decision-making and provides transparent insights into how alternative vaccination strategies may shape pertussis dynamics. Combining accessibility, flexibility, and methodological rigour, PerTexP offers a practical resource for researchers and public health practitioners interested in exploring and comparing pertussis control strategies.
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