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Molecular characterisation of a Klebsiella pneumoniae neonatal sepsis outbreak in a rural Gambian hospital: a retrospective genomic epidemiology investigation
2026-03-04
genetic and genomic medicine
Title + abstract only
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BackgroundKlebsiella pneumoniae is a common cause of neonatal sepsis in Africa, and is frequently hospital acquired. We recently reported an outbreak of multidrug-resistant K. pneumoniae sepsis amongst neonates at a rural hospital in The Gambia, West Africa, involving 57 cases and case fatality of 60%. Here we undertook a retrospective pathogen genomic epidemiology study of clinical and environmental K. pneumoniae isolated during the outbreak, to identify the outbreak strain, refine the epidemic...
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